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Tom Holland as Peter Parker/Spider Man

Bella Thorne as Mary Jane Watson

Jon Hamm as Norman Osborn

Dave Franco as Harry Osborn

Jacob Batalon as Ned Leeds

Marisa Tomei as May Parker

Aaron Eckhart as Curt Connors/The Lizard

Michael Mando Mac Gargan/Scorpion

Dominic Purcell as Aleksei Sytsevich/The Rhino

Michael Chernus as Phineas Mason/Tinkerer

Mark Ruffalo as Bruce Banner/Hulk

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