Peter Parker was born to Richard and Mary Parker, and raised to the age of 8. When he was small, his parents had to leave for an unknown reason, and he was left with Richard's brother Ben and his wife May.
Six years later, during a field trip to Oscorp, Peter was bitten by a radioactive spider and attained the strength agility of a spider. After misusing his powers for two weeks, his Uncle Ben was shot by a robber that he let run past him while angry. After hunting down the robber, Peter swore to follow his Uncle's golden rule: "With Great Power Comes Great Responsibility"